“Satan trembles when he sees the weakest saint upon his knees”(A. T. Robertson).
Prayer is powerful, and the enemy is terrified by it! We are told in James 5: 16, “The effective, fervent prayer of a righteous man avails much.” In Ephesians 6: 18, Paul instructs the believer to “Pray at all times, in the Spirit …” What is meant by the phrase “in the Spirit?”
There are some who teach that praying in the Spirit is the same as praying in tongues. Not so; while tongues are a valid gift of the Spirit (1Corinthiens 12: 8-11) it is not a fruit of the Spirit (Galatians 5:22-23). Not every believer speaks in tongues. But Paul instructs the believer to pray in the Spirit on all occasions. (Ephesians 6: 18). Since all true believers bare the fruit of the Spirit but not all speak in tongues, we can conclude that praying in the Spirit, is distinct form praying in tongues (Christianity.com).
What then, is praying in the Spirit? It is, as I understand, prayer rendered with divine help. It is prayer that flows from a true heart, a right spirit, and without hypocrisy. It is the prayer offered with fervency and influenced by the work of the Holy Spirit. It is, for this reason, the enemy trembles in fear when the believer – even the weakest – kneels to pray.
So, let us pray at every opportunity, with fervency – in the Spirit, and see the enemy flee!